Pathophysiology 1) usually congenital saccular dilation of artery in brain 2) most commonly located at bifurcations of cerebral arteries … [Read more...]
Wegener’s Granulomatosis
Pathophysiology 1) necrotizing granulomatous disease of the upper and lower respiratory tract in setting of glomerulonephropathy 2) most cases have … [Read more...]
Amyloidosis
Pathophysiology 1) deposition of fibrous, insoluble amyloid protein in extracellular matrices of body 2) clinically ranges from benign to severe … [Read more...]
Raynaud’s Phenomenon
Pathophysiology 1) intermittent ischemia of fingers and toes 2) if occurs as an isolated event, then it is called Raynaud's disease or primary … [Read more...]
Reiter’s Syndrome
Pathophysiology 1) a type of spondyloarthropathy 2) marked by arthritis nongonococcal urethritis or cervicitis, and conjunctivitis Signs and … [Read more...]
Crohn’s Disease
Pathophysiology of Crohn's disease 1) Crohn's disease is marked by transmural inflammatory disease of the GI tract (may involve other organs) GI … [Read more...]
von Willebrand’s Disease
Pathophysiology 1) type of bleeding disorder (can be inherited or acquired) due to a defect in, or reduction of, von Willebrand factor 2) four … [Read more...]
Gaucher’s Disease
Pathophysiology 1) metabolic disease due to defect in beta-glucocerebrosidase (beta-glucosidase) Type 1 - 2) adult onset, chronic, highly variable … [Read more...]
Sickle Cell Disease
Pathophysiology 1) family of hemoglobinopathies with deformation of deoxygenated erythrocytes into a sickle shape 2) homozygous individuals are … [Read more...]
Mononucleosis
Pathophysiology of Mononucleosis Mononucleosis is an infection with Epstein-Barr virus (or sometimes CMV with slightly different clinical … [Read more...]
Homocystinuria
Pathophysiology 1) group of seven different disorders 2) most common variant is caused by deficiency in cystathionine-beta-synthase 3) thought to … [Read more...]
Farber’s Disease
Pathophysiology of Farber's Disease Farber's disease is disseminated lipogranulomatosis of infancy and early childhood owing to defect in … [Read more...]
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