Charcot's triad - right upper quadrant pain, fever, jaundice … [Read more...]
Crohn’s Disease
Pathophysiology of Crohn's disease 1) Crohn's disease is marked by transmural inflammatory disease of the GI tract (may involve other organs) GI … [Read more...]
Gardner’s Syndrome
Pathophysiology 1) hereditary polyposis coli syndrome with large and small bowel carpeted by adenomatous polyps 2) occurs in association with other … [Read more...]
Pancreatic Cancer (ductal adenocarcinoma)
Pathophysiology 1) development of solid tumor originating from ductal system 2) metastases are most common to liver and regional lymph … [Read more...]
Acute Cholecystitis
Pathophysiology 1) inflammation of gallbladder 2) causes are obstructing calculi in cystic duct (95%) and bile stasis (occurs in critically ill … [Read more...]
Pernicious Anemia
Pathophysiology 1) cause - lack of intrinsic factor in gastric secretions 2) adult form - deficiency of intrinsic factor owing to gastric atrophy … [Read more...]
Hepatic Encephalopathy
Pathophysiology of Hepatic Encephalopathy Hepatic encephalopathy is a: 1) neuropsychiatric disturbance caused by cirrhosis/hepatocellular … [Read more...]
Achalasia
Achalasia is a disease of the esophagus marked by difficulty swallowing Pathophysiology 1) chronic, usually progressive, disorder of myenteric … [Read more...]
Crigler-Najjar Syndrome
Pathophysiology 1) autosomal recessive inability of liver to conjugate bilirubin 2) type 1 - more severe; enzyme that conjugates bilirubin is … [Read more...]
Wilson’s Disease
Pathophysiology 1) copper accumulation in the liver, corneas, brain, and kidneys owing to inadequate biliary copper excretion 2) two forms - … [Read more...]
Acute Cholecystitis – 4 Fs
Characteristics of patients that commonly develop acute cholecystitis - 4 Fs Female, fat, fertile, and forty … [Read more...]
Hemochromatosis
Pathophysiology 1) systemic tissue damage caused by excess iron 2) occurs in primary form (due to increased iron absorption with deposition in … [Read more...]