Pathophysiology
1) development of solid tumor originating from ductal system 2) metastases are most common to liver and regional lymph nodes
Signs and Symptoms
1) abdominal pain (gnawing or burning nature typically) 2) jaundice 3) enlarged, palpable gallbladder in 40% of patients (Courvoisier’s sign) 4) light-colored stools 5) dark urine 6) pruritus 7) weight loss 8) splenomegaly 9) venous thrombosis 10) migratory thrombophlebitis (Trousseau’s sign)
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