Absence of fructose-1-phoshpate liver aldolase in kidney, liver, and small bowel; marked by vomiting, convulsions, cachexia, hepatomegaly, jaundice, edema, and ascites. Autosomal recessive condition manifests in infancy when fructose or sucrose is 1st ingested. Treatment is fructose-free diet and liver transplantation (if liver failure occurs).