{"id":8007,"date":"2013-03-09T11:39:04","date_gmt":"2013-03-09T16:39:04","guid":{"rendered":"http:\/\/insidesurgery.com\/?p=8007"},"modified":"2013-03-10T19:36:50","modified_gmt":"2013-03-10T23:36:50","slug":"patent-ductus-arteriosus","status":"publish","type":"post","link":"https:\/\/insidesurgery.com\/2013\/03\/patent-ductus-arteriosus\/","title":{"rendered":"Patent Ductus Arteriosus"},"content":{"rendered":"
1)<\/strong> patent ductus arteriosus is failure of closure of ductus arteriosus (which during fetal development shunts blood around the lungs from the pulmonary artery to the aorta) in the first few days of life<\/strong> <\/p>\n
\n 2)<\/strong> causes an initial left-to-right shunt (flow from high-pressure aorta to low-pressure pulmonary artery
\n3)<\/strong> eventually progresses to Eisenmenger’s syndrome<\/a> (pulmonary hypertension with reversal of flow and a right-to-left shunt with blood moving from pulmonary artery to aorta)
\n4)<\/strong> conditions that delay closing are hypoxemia, acidosis, prematurity
\n5)<\/strong> death in patent ductus arteriosus is from cardiac failure or infective endocarditis<\/p>\n