{"id":6676,"date":"2012-11-10T10:28:02","date_gmt":"2012-11-10T15:28:02","guid":{"rendered":"http:\/\/insidesurgery.com\/?p=6676"},"modified":"2013-05-18T23:45:34","modified_gmt":"2013-05-19T03:45:34","slug":"mannitol-administration","status":"publish","type":"post","link":"https:\/\/insidesurgery.com\/2012\/11\/mannitol-administration\/","title":{"rendered":"Mannitol Administration"},"content":{"rendered":"<p>Although lacking level 1 support, mannitol is an commonly used drug in cases of severe traumatic brain injury to manage an increase in intracerebral pressure (ICP).<\/p>\n<p><!--more--><\/p>\n<p>The standard dilution used is a 25% solution with 12.5 g in a 50 ml vial. A 5 micron conical filter is typically used to draw up the solution and the drug is given via slow IV push.<\/p>\n<p>The dose varies on the clinical setting but usually aim is a serum osmolarity &gt; 320. If the serum osm is less than 320 a typical regimen is 50 g q 4-6 hours.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Although lacking level 1 support, mannitol is an commonly used drug in cases of severe traumatic brain injury to manage an increase in intracerebral pressure (ICP).<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[5062,5072,13],"tags":[5075,5074,5073,5008],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mannitol Administration - 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