Tumoral calcinosis is a rare condition first described in 1899 and given the current name by Inclan and colleagues in 1945 and describes the formation of peri-articular deposits around joints, typically the shoulders, elbows, hips, and sometimes knees.<\/p>\n
Alternate names used to describe this condition are Teutschlander disease, calcifying bursitis, hip-stone disease, hydroxyapatite disease, and pseudotumoral calcinosis<\/p>\n
Histologically, the deposits are most typically calcium hydroxyapatite crystals surrounded by giant cell reaction with hisitocytes.<\/p>\n
The most common presentation is of a single, painless, periarticular mass that may interfere with joint range of motion. However, the joint itself is universally found to be uninvolved which helps to distinguish tumoral calcinosis from pseudogout and idiopathic synovial chondromatosis.<\/p>\n
Epidemiologically patients generally fall into one of three classifications – 1) dialysis-dependent renal patients (most common); 2) patients with familial derangements of phosphorus and vitamin D; and 3) idiopathic presentation in patients with no known metabolic derangements.<\/p>\n
The disease is more common in men and African Americans and is thought to affect about 1% of the dialysis population.
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The laboratory derangements (if present) are marked by increased serum 1,25 dihydroxy-vitamin D and abnormal serum phosphorus levels (usually elevated>)<\/p>\n","protected":false},"excerpt":{"rendered":"
Tumoral calcinosis is a rare condition first described in 1899 and given the current name by Inclan and colleagues in 1945 and describes the formation of peri-articular deposits around joints, typically the shoulders, elbows, hips, and sometimes knees. Alternate names used to describe this condition are Teutschlander disease, calcifying bursitis, hip-stone disease, hydroxyapatite disease, and […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[63],"tags":[3998,3999,3997,4000,3994],"yoast_head":"\n