{"id":273,"date":"2006-11-23T00:21:00","date_gmt":"2006-11-23T07:21:00","guid":{"rendered":"http:\/\/wp.onegoodcookie.com\/?p=273"},"modified":"2006-11-23T00:21:00","modified_gmt":"2006-11-23T07:21:00","slug":"november-23-2006","status":"publish","type":"post","link":"https:\/\/insidesurgery.com\/2006\/11\/november-23-2006\/","title":{"rendered":"November 23, 2006"},"content":{"rendered":"
Seizures in the ICU – Part 4<\/b><\/p>\n
Status epilepticus has several cellular manifestations that cause damage to the surrounding brain tissue secondary to the opening of ion channels coupled to excitatory amino acid (EAA) receptors. These include:<\/p>\n
\n1. Increased swelling of neurons secondary to increased intracellular osmolality<\/p>\n
2. Generation of toxic concentrations of intracellular free calcium<\/p>\n
3. Activation of autolytic enzyme systems<\/p>\n
4. Phosphorylation of enzyme systems, making further seizures more likely<\/p>\n
5. Production of oxygen free radicals<\/p>\n
6. Activation of autolytic enzyme systems<\/p>\n
Copyright 2006 Insidesurgery.com<\/p>\n","protected":false},"excerpt":{"rendered":"
Seizures in the ICU – Part 4<\/b><\/p>\n
Status epilepticus has several cellular manifestations that cause damage to the surrounding brain tissue secondary to the opening of ion channels coupled to excitatory amino acid (EAA) receptors. These include:<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[13],"tags":[],"yoast_head":"\n