{"id":233,"date":"2006-10-14T08:47:25","date_gmt":"2006-10-14T15:47:25","guid":{"rendered":"http:\/\/wp.onegoodcookie.com\/?p=233"},"modified":"2006-10-14T08:47:25","modified_gmt":"2006-10-14T15:47:25","slug":"october-14-2006","status":"publish","type":"post","link":"https:\/\/insidesurgery.com\/2006\/10\/october-14-2006\/","title":{"rendered":"October 14, 2006"},"content":{"rendered":"<p><b>Nitroprusside and Cyanide Toxicity &#8211; Part 4<\/b><\/p>\n<p>Treatment of cyanide toxicity begins with discontinuation of sodium nitroprusside administration. Patients should be concomitantly placed on supplemental oxygen and may even require mechanical ventilation. Additionally, thiosulfate and sodium nitrate (to convert hemoglobin to methemoglobin) can be given to increase the kinetics of the other metabolic pathways, resulting in less cyanide being available to bind to cytochrome oxidase. Additionally, thiosulfate can be given concomitantly with with nitroprusside to lessen the risks of cyanide toxicity from developing.<\/p>\n<p>Copyright 2006 Insidesurgery.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nitroprusside and Cyanide Toxicity &#8211; Part 4 Treatment of cyanide toxicity begins with discontinuation of sodium nitroprusside administration. Patients should be concomitantly placed on supplemental oxygen and may even require mechanical ventilation. Additionally, thiosulfate and sodium nitrate (to convert hemoglobin to methemoglobin) can be given to increase the kinetics of the other metabolic pathways, resulting [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[13],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>October 14, 2006 - InsideSurgery Medical Information Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/insidesurgery.com\/2006\/10\/october-14-2006\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"October 14, 2006 - InsideSurgery Medical Information Blog\" \/>\n<meta property=\"og:description\" content=\"Nitroprusside and Cyanide Toxicity &#8211; Part 4 Treatment of cyanide toxicity begins with discontinuation of sodium nitroprusside administration. 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