{"id":2113,"date":"2009-12-30T22:33:46","date_gmt":"2009-12-31T03:33:46","guid":{"rendered":"http:\/\/insidesurgery.com\/?p=2113"},"modified":"2009-12-30T22:59:17","modified_gmt":"2009-12-31T03:59:17","slug":"bronchitis","status":"publish","type":"post","link":"https:\/\/insidesurgery.com\/2009\/12\/bronchitis\/","title":{"rendered":"Bronchitis"},"content":{"rendered":"

Pathophysiology<\/strong><\/p>\n

chronic irritation of bronchioles defined as cough and production of sputum on the majority of days in a 2 year period without any identifiable cause<\/p>\n

Signs and Symptoms<\/strong><\/p>\n

1)<\/strong> cough 2)<\/strong> production of excess sputum 3)<\/strong> exertional dyspnea 4)<\/strong> cyanosis 5)<\/strong> cor pulmonale 6)<\/strong> edema 7)<\/strong> progressive hypoxemia 8)<\/strong> hypercapnia<\/p>\n

Characteristic Test Findings<\/strong><\/p>\n

Laboratory<\/em> – Reid’s index (measure of size increase in mucous glands) is > .5 (normal is < .5)\n\nHistology\/Gross Pathology<\/strong><\/p>\n

1)<\/strong> hypertrophy of mucus-secreting glands 2)<\/strong> increased proportion of mucous cells to serous cells 3)<\/strong> thickened bronchial wall 4)<\/strong> increase in smooth muscle and chronic inflammation in submucosa 5)<\/strong> squamous metaplasia of bronchial epithelium<\/p>\n

Associated Conditions<\/strong><\/p>\n

1)<\/strong> > 90% of patients are smokers and also have COPD 2)<\/strong> air pollution with inhalation of sulfur dioxide and particulate matter 3)<\/strong> cystic fibrosis 4)<\/strong> infections – Nocardia<\/em>, Haemophilus influenzae<\/em>, Streptococcus pneumoniae<\/em>, adenovirus<\/p>\n

Treatment<\/strong><\/p>\n

1)<\/strong> strict abstinence from smoking 2)<\/strong> antibiotics for pulmonary infections 3)<\/strong> bronchodilator drugs<\/p>\n

Tips for USMLE<\/strong> <\/p>\n

1)<\/strong> if a Reid’s index > 0.5 is mentioned, think bronchitis 2)<\/strong> if “blue bloater” is mentioned (cyanosis and edema associated with cor pulmonale), think bronchitis<\/p>\n","protected":false},"excerpt":{"rendered":"

Pathophysiology chronic irritation of bronchioles defined as cough and production of sputum on the majority of days in a 2 year period without any identifiable cause Signs and Symptoms 1) cough 2) production of excess sputum 3) exertional dyspnea 4) cyanosis 5) cor pulmonale 6) edema 7) progressive hypoxemia 8) hypercapnia Characteristic Test Findings Laboratory […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[63],"tags":[763,761,765,762,764],"yoast_head":"\nBronchitis - InsideSurgery Medical Information Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/insidesurgery.com\/2009\/12\/bronchitis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bronchitis - 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