Ranson’s criteria is a measure of eleven clinical measures that is used to predict severity and mortality in acute pancreatitis from both gallstone and alcohol etiologies. It was developed in 1974 and although still widely used has been shown through meta-analysis to correlate poorly with actual outcomes. There are five clinical values that are obtained at admission and six at 48 hours after admission. These are: Admission 1. Blood glucose > 200mg/dL 2. Age > 55 years 3. LDH > 350 IU/L 4. Serum AST > 250 IU/L 5. White blood cell count > 16,000 cells/mm3 At 48 hours 1. Calcium deceased of 2.0 or total < 8.0 mg/dL 2. Hematocrit decrease > 10% 3. Oxygen serum level < 60 mmHg 4. BUN increase > 5 mg/dL or 1.8 mmol/L 5. Base deficit > 4mEq/L 6. Sequestration of fluids > 6L Ranson’s criteria mortalilty prediction is: 0-2: 2% mortality 3-4: 15% mortality 5-6: 40% mortality above 7: 100% mortality