Hereditary polyposis syndrome with numerous hamar-tomas in stomach as well as in small and large intestine that can cause bleeding, obstruction, and intussusception; associated with characteristic pigmentation of buccal skin and also of fingers, toes, umbilical area, and forearm, which may recedo at puberty. Polyps usu. occur after onset of pigment changes. Tumors of breast, ovary, uterus, and pancreas may develop; controversy exists regarding malignant potential. Condition is autosomal dominant.