Plasma cell dyscrasia with severe, progressive motor polyneuropathy; polyneuropathy, organomegaly, endocrinopathy, M-proteins, and skin changes. Condition is marked by anasarca of legs, diffuse hyperpigmentation, hypertrichosis, ascites, pleural effusion, fever, finger clubbing, lymphadenopathy, hepatomegaly, hyperhidrosis, and gynecomastia. Treatment is prednisone, radiation, and cyclophosphamide. Death occurs 2Ð3 years after onset.