An experimental drug has been shown to reverse Alzheimer’s type learning deficits in mice. The study was done by Yale University’s Dr. Paul Lombroso and published in PLoS Biology.
The drug was found by screening 150,000 potential inhibitors of the protein striatal enriched protein tyrosine phosphatase (STEP.) Eight compounds were selected for testing with the drug dubbed TC-2153 showing the most pronounced effect.
The researchers will next try to duplicate their results in rats and higher non-primate animals.