Category Archives: Drug-Drug Interactions

A 68 year old diabetic man was restarted post-operatively on his normal dose of the blood thinner Coumadin (warfarin) for his chronic, intermittent atrial fibrillation. He had received a femoral tibial bypass for severe peripheral vascular disease and gangrene of his first and second toe on the right foot. His post-operative antibiotics included a 10 day course of metronidazole (Flagyl) and cefotetan to provide broad-spectrum coverage for his infected foot. The

A 56 year old male smoker receives a liver transplant secondary to his advanced stage alcoholism and hepatitis C infection. The transplant surgery takes longer than expected and at post-operative Day 6 the patient is still in the intensive care unit. His transplanted liver is working well and he is on the standard immunosuppression regimen of tacrolimus and steroids. Because his lung function